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外周血嗜酸细胞计数在条件免疫反应哮喘动物模型的变化观察

The observation on the changes in the counts of peripheral eosinophils of asthma animal models with conditioned immunoreaction

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【作者】 张晓奇刘雅琴曾常茜王淼李玉英

【Author】 Zhang XiaoQi,(Department of neurology;the Affiliated Hospital of Jinlin Medical College.Jinlin 132001)

【机构】 吉林医学院附属医院神经内科吉林医学院免疫教研室吉林省医院电诊室

【摘要】 目的:观察嗜酸细胞数在条件免疫反应哮喘动物模型的变化。方法:对经过条件刺激和未进行条件刺激的各组动物予以心脏采血,做血图片。Wright 氏染色,放于光镜下计数。结果:CS1、CS2、NS1三组嗜酸细胞计数结果无明显差异 P>0.05;CS3、NS2□两组嗜酸细胞计数结果无明显差异 P>0.05 CS1、CS2与 CS3比较 P<0.01有显著差异;NS1与 NS2比较 P<0.01有显著差异;CS1、CS2、NS1与 CS3、NS2比较 P<0.01有显著差异。结论:嗜酸细胞计数变化不随条件刺激的存在或不存在而改变,而与哮喘发作次数有关。

【Abstract】 Objective:To observe the changes in the counts of eosinophils of asthma animal models with conditioned immunoreaction.Methods:Blood samples collected from the hearts of animals in CS groups and non-CS groups were smeared and stained with wright’s method and then counted under light microscope.Result: There were no significant differences in eosinophils counting between CS1.CS2 and NSl groups (P>0.05).There was no significant difference betwween CS3 and NS2 (P>0.05).The difference was significant between CS1.CS2 groups and CS2 group.(P<0.01) and also between NSl and NS2.There were significant differences between CS1 CS2 NSl and CS3.NS2(P<0.01).Conclusion:The eosinophil counting does not vary with the presence or absence of CS but is associated with the times of asthma attack.

【基金】 吉林省教育委员会资助项目
  • 【文献出处】 吉林医学院学报 ,Journal of Jilin Medical College , 编辑部邮箱 ,1999年03期
  • 【分类号】R562.25
  • 【下载频次】41
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