【摘要】 了解苯那普利(benazapril)的降低慢性肾小球肾炎原蛋白的作用。方法:对慢性肾炎病人64例进行多中心自身对照观察。结果:经苯那普利治疗12周后,大量蛋白尿组(30例)尿蛋白下降47.0%,小量蛋白尿组(34例)尿蛋白下降 47.5%,平均起效时间分别为( 5.1±3. 2)周(大量蛋白尿组)和( 2. 7±2. 1)周(小量蛋白尿组),同时,其中14例肾病综合征患者的低白蛋白血症也有明显改善。结论:苯那普利可部分地降低慢性肾小球肾炎患者的尿蛋白。更多还原

【Abstract】 To investigate the effect of benazepril on proteinuria in patients with chronic glomerulonephritis. Methods: A multi-centered and self-controlled study was performed and 64 patients with chronic glomerulonephritis were included. Results:After 12 weeks of treatment, urinary protein decreased by 47. 0 % and 47. 5 % in heavy proteinuria group (30 cases) and in mild proteinuria group (34 cases), respectively. Significant improvement of hypoalbuminemia was found in 14 patients with nephrotic syndrome. Conclusion: Benazepril can significantly decrease proteinuria in patients with chronic glomerulonephritis.更多还原