【摘要】 目的 :观察复方丹参注射液对硝酸甘油 (NTG)控制性降压时动脉血气改变的影响。方法 :1 6例在全身麻醉、控制性降压下择期手术的成人患者 ,随机分成对照组与丹参组(各 8例 )。两组均用NTG控制性降压 ,血压下降幅度约为对照值的 3 0 % ,丹参组在降压前静脉注射复方丹参注射液 1 6ml。结果 :对照组在降压期间动脉血氧分压 (PaO2 )显著下降 ,动脉血于呼气末二氧化碳分压差 (Pa etCO2 )显著升高 ,而丹参组血气无显著性改变。结论 :复方丹参注射液可预防NTG对血气的不良影响。更多还原

【Abstract】 Objective: To observe the effects of Salvia Miltiorrhizae Composita (SMC) on blood gas variations of nitroglycerin (NTG) controlled hypotension. Methods: Sixteen patients who were arranged to undergo operation under general anesthesia in controlled hypotension condition were divided randomly into control group (n=8) and SMC group (treated group, n=8), NTG were used to create controlled hypotension in both groups and blood pressure decrease about 30% comparing with the control values. Patients in the treated group were administered intravenously with SMC (16 ml) before the utilization of NTG. Results: Significant PaO 2 decrease and Pa etCO 2 increase were observed in the control group during the controlled hypotension period. However, blood gas values in the treated group did not evidently change.Conclusion: It suggested that SMC can prevent the side effects of NTG on blood gas.更多还原