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菊苣正己烷提取物药理活性研究

Study on Pharmacological Activity of Extract from Herba Cichorii

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【作者】 张冰胡京红刘小青杜海燕郑红梅

【Author】 Zhang Bing,Hu Jinhong,Liu Xiaoqing,Du Haiyan,Zhen Hongmei (Beijing University of Traditional Chinese Medicine Beijing 100029)

【机构】 北京中医药大学中药学院

【摘要】 从菊苣(HerbaCichori)提取到一种白色结晶,该成分可降低四氧嘧啶模型小鼠血糖及血清甘油三酯水平,对抗高糖高脂血清导致的兔主动脉平滑肌细胞损伤,改善平滑肌细胞膜微粘度,降低培养液中过氧化脂质浓度。

【Abstract】 The article observed pharmacological activity of extract which is a white crystal substance and extracted from n hexane part of herba cichorii in vitro and in vivo.The result shows that the extract lowers the level of blood sugar and triglyceride in alloxane model mouse.It also demonstrated that the extract antagonizes rabbit aortic smooth muscles injury result in hyperlipidemic and hyperglycemic culture medium by lowering lipid peroxide in medium and recovering membrance fluidity.So,it is considered that extract be a active component of herba cichorii to reduce blood sugar and lipid in clinic.

【关键词】 菊苣降血糖
【Key words】 Herba Cichoriiblood sugarLPO
【基金】 国家科委资助
  • 【文献出处】 中药药理与临床 ,PHARMACOLOGY AND CLINICS OF CHINESE MATERIA MEDICA , 编辑部邮箱 ,1998年05期
  • 【分类号】R285.5
  • 【被引频次】28
  • 【下载频次】232
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