【摘要】 目的:载瘤动脉间断阻断是一种新型的辅助技术,在颅内动脉瘤夹闭术中有着相当大的实用性。方法:通过建立大鼠可复流的脑缺血—再灌注病理模型,探讨了间断阻断大脑中动脉安全阻断时间,间断阻断10min,复流5min。结果:在1h内不会造成明显的缺血性损伤和病理学体征。结论:此种方法如能与其它脑保护措施联合应用,将能发挥更大作用。更多还原

【Abstract】 To test the safe time limite of intermittent middle cerebral artery occlusion. Method: Intermittent MCA occlusion was studied by using a reflow permissible cerebral is-chemic reperf usion model in rat. Result: This experiment showed that 60 minutes intermittent occlusion with 5 minutes reperfusion after each 10 minutes ischemic period was well tolerated without obvious ischemic neurological deficits. Conclusion: The middle cerebral artery of rats can tolerate safely for 60 minutes intermittent occlusion. If neuroprotective procedure were used, the results mav even be better.更多还原