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乙型和庚型肝炎病毒感染与肝细胞癌血清流行病学研究

A Seroepidemiology Study on HBV,HGV and HCC

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【作者】 方顺源蔡一华汪志强黄志成王一泓许珂

【Author】 Fan Shunyan,et,al;Hangzhou Sanitation and Anti-epidemic Station,Hangzhou(310006)

【机构】 杭州市卫生防疫站

【摘要】 为探讨乙型和庚型肝炎病毒(HBV和HGV)感染与肝细胞癌(HCC)发生的关系,采用酶联免疫吸附法(ELISA)和聚合酶链反应(PCR)对85例HCC患者血清进行了HBV和HGV血清标志和HGVRNA检测,结果HCC患者中HBV感染率为77.65%;HGV感染率为27.06%,HGV和HBV重叠感染率(22.35%)明显高于HGV单独感染率(4.71%)。结果提示:HBV感染为HCC发生的重要原因;HGV感染可能参与HCC的发生;而HGV和HBV重叠感染是否有可能增加HCC的发生,值得进一步探讨

【Abstract】 To study the relation between the infection of HBV & HGV and HCC occurring.The serum mark of HBV & HGV and the detection of RNA & HGV in 85 patients with HCC is seram made were ELISA and PCR.The rate of infection of HBV in patients with HCC and HGV in patients with HCC were 77.65%,27.06% respectively.The rate of overlapping infection of HGV and HBV(22.35%) was significantly higher than that of HGV(471%).The results indicated thet HBV infection was the main cause of HCC occurring and the infection of HGV may take part in the HCC occurring.It was needed further study that if the overlapping infection of HGV and HBV probably increasing the risk of HCC occurring.

【关键词】 乙型肝炎病毒庚型肝炎病毒肝细胞癌
【Key words】 HBV\ HGV\ HCC
  • 【文献出处】 中国慢性病预防与控制 ,CHINESE JOURNAL OF PREVENTION AND CONTROL OF CHRONIC NON-COMMUNICABLE DISEASES , 编辑部邮箱 ,1998年04期
  • 【分类号】R512.62
  • 【被引频次】3
  • 【下载频次】18
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