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BCG,BCG+IL-2膀胱灌注预防膀胱癌复发的疗效评价
BCG,BCG and IL-2 intravesical instillation in the prevention of postopcrative recurrence of bladder tumor
【摘要】 本文对BCG,BCG+IL-2膀胱灌注预防膀胱癌术后复发的疗效进行了分析,74例膀胱癌分为两组。一组40例单用BCG(150mg),另一组34例BCG(100mg)+IL-2(20000Iu)。BCG组随访18~72月,平均30.9月,无肿瘤复发率80%(32/40),BCG+IL-2组随访16~7O月,平均29.4月,无肿瘤复发率88.3%(3O/34),两组比较有显著性(P<0.01)。结果表明,无论单独用BCG或BCG+IL-2联合应用,疗效都十分肯定,而BCG+IL-2组更优,可减少BCG用量,毒副反应小。
【Abstract】 Railway Medical College in Xuzhou, Xuzhou 221009For the prevention of tumor recurrence,intravesical instillation of only 150mg BCGwas instituated postoperatively in 40 cases of bladder cancer and intravesical instillationof a combination of 20000 unites of IL-2 and 100mg of BCG in another 34. In the BCGgroup, 80% (32/40) have been free of tumor for a mean time of 30. 9 months (follow upranging from 18 to 72 months) and in the combination of BCG and IL-2 group, 88. 3%(30/34) have been free of tumor for a mean time of 29. 4% months (follwo up rangingfrom 16 to 70 months). Comparing the results of two groups, it is striking (P<0.01).The results revealed that BCG or combination BCG and IL-2 intravesilal instillation inthe prevention of tumor recurrence, which effect were very definited. The later groupwhat is more dominant, it decreased the dose of BCG and the side-effect minor.
- 【文献出处】 肿瘤防治研究 ,CANCER RESEARCH ON PREVENTION AND TREATMENT , 编辑部邮箱 ,1998年04期
- 【分类号】R737.14
- 【下载频次】28