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肾细胞癌微血管分布形态及定量的病理学研究

Microvessal quantitation and morphology pathologic study in renal cell carcinoma

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【作者】 耿敬姝鄢明明王艳颖

【Author】 Geng Jingshu,et al(Depart. of Pathology,Tumor Hospital,Harbin Medical Univertvity, Harbin 150040)

【机构】 哈尔滨医科大学附属第三医院!150040哈尔滨医科大学附属第一医院!150040

【摘要】 用FⅧ相关抗原免疫组化染色观察48例肾细胞癌组织内微血管的四种类型(即包绕型、乳头轴心分布型、海绵样腔隙型及弥漫裂隙型)的分布,并对其进行定量分析。结果表明:随着组织学分级的增高微血管密度增加(P<0.01),且在组织学Ⅰ级中无弥漫裂隙型分布,而在Ⅲ级中则均为弥漫裂隙型分布。同时结果还提示,肾细胞癌微血管的密度及弥漫裂隙型分布与肾细胞癌其它脏器的血行转移关系密切。

【Abstract】 Microvessal quantitation and morphology in 48 patients with renal cell carcinoma was analyzed by immunohistochemistry using antibody to facto Ⅷ-related antigen. The result showed that:there were four types in microvessal morphology. Microvessal quantitation much more in the high histological grade(P<0.01).There was no diffuse interstice type found in histological grade I specimens and only it was obsened in grade Ⅲ.The result also suggested that the microvessal quantitation and the presence of diffuse interstice type may have a close correlation to the blood metastasis to other organs in renal cell carcinoma.

【关键词】 肾细胞癌微血管形态定量
【Key words】 renal cell carcinomamicrovessal morphologyquantitation
  • 【文献出处】 肿瘤防治研究 ,CANCER RESEARCH ON PREVENTION AND TREATMENT , 编辑部邮箱 ,1998年02期
  • 【分类号】R737.11
  • 【被引频次】4
  • 【下载频次】28
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