【摘要】 40例中晚期原发性肝癌患者应用小剂量醛氢叶酸合并FM或FAM方案静脉化疗。结果显示部分缓解12例（30％），8例存活期超过一年，其中2例分别超过34个月和48个月。表明该方法治疗原发性肝癌有一定的疗效。并值得结合手术和2p-TAE术一起应用，在减少或预防肝癌肝外转移，提高远期生存率方面做进一步的探讨。更多还原

【Abstract】 Forty patients with primary hepatocellular carcinoma were treated with low does CF(LDCF) andFM or FAM Chemotherapy regimens, the does Of CF is 20mg/m2/d for 5 days, other chemotherapeuticdrugs are usual doeses and usage. Each patient was treated two or over two courses. The results showedthat the therapeutic effective rate was 30% (12/40), 8 cases survived more than 12 months; amongthem, 1 survived more than 34 months and another survived more than 46 months. It suggested thatLDCF plus FM or FAM has a clinic significance for treatment of advanced hepatocellular carcinoma andmay be try tO prevent extraheptic metastasis.更多还原