【摘要】 了解临床甲减病人血中甲状腺素自身抗体（T4Ab）及3，5，3’-三碘甲状腺原氨酸自身抗体（T3Ah）分布状况。方法：采用放射免疫法测定120例原发性甲减患者的T3Ab、T4Ab。结果：甲减患者T3Ab、T4Ab的测定值分别为9．42±4．43％及10．73±4．67％．较正常组升高非常显著（n=120．P＜0．01）；其T3Ab、T4Ab的阳性率分别为37．50％及40．83％。对甲减分组，伴TGAb和（或）TMAb升高组的T3Ab、T3Ab测定值及阳性率均较不升高组显著升高（P＜0．01）。结论：T3Ab、T4Ab在原发性甲减患者血中阳性率较高．其测定有助于甲减的诊断。更多还原

【Abstract】 Objective To investigate the prevalence of anti-triiodothyronine antibody(T,Ab) and anti-thyroxine antibody(T.Ab) in patients with hypothyroidism and explore their clinical significance. Methods: T3Ab andT4Ab were measured in 120 patients with hypothyroidism by radioimmunoassay. Results: The levels of T3Ab andT4Ab were 9. 42± 4. 43 % and 10. 73±4. 67 % respectively, which were significantly higher than those in normal controls(n= 120,P<0. 01 ). The positive rates of T3Ab and T4Ab for patients with hypothyroidism were37. 5% and 40. 83% respectively. The levels and positive rates of thyroid hormone autoantibodies in patientswith increased antithyroglobulin antibody(TGAb) and /or antimicrosomal antibody(TMAb) were significantlyhigher than those with normal TMAb and TGAb(P<0. 01 ). Conclusion:The POsitive rates of T3Ab and T.Abin hypothyroidism are high and the measurement of T3Ab and T4Ab may be helpful for diagnosis of hypothyroidism.更多还原