【摘要】 目的动态观察兔眼人工晶体植入术后晶体表面细胞反应及膜形成，探讨术后早期膜形成的机制及生物学作用。方法２０只兔眼行后房型人工晶体植入术，分别于术后１、３、７、１４及２８天分组取出人工晶体，做光镜及扫描电镜检查。结果术后３天人工晶体表面巨噬细胞开始转化为成纤维细胞样细胞并有嗜伊红薄膜形成，扫描电镜下细胞间有细丝相连形成具有网状支架的薄膜。结论推测人工晶体表面膜是人工晶体表面的成纤维细胞样细胞分泌的一种纤维蛋白性膜。参与反应的细胞是膜形成的生物学基础。这种膜可以抑制强烈的细胞反应，维持人工晶体的透明性更多还原

【Abstract】 Objective To observe the cellular reaction and membrane formation on the surface of intraocular lens (IOL) implanted in rabbit eyes and discuss the mechanism of early postoperative membrane formation and biological action. Methods 20 adult pigmented rabbit eyes were given posterior chamber IOL implantation. IOLs were extracted on the postoperative 1st, 3 rd, 7th, 14th and 28th days respectively. Samples were observed under light microscope and scanning electron microscope (SEM). Results Macrophages on the surface of IOL had transformed into fibroblast like cells and the formation of eosinophilic membrane had occurred on the 3rd day after operation with tiny thread like things interwoven among cells forming net like supporting membrane under SEM. Conclusion It infers that the membrane is a kind of fibrinous film secreted by fibroblast like cells and the cells involved in reaction are the biological foundation of membrane formation; this membrane will prohibit the serious cellular reaction at the end and keep IOL transparent.更多还原