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冠心病心绞痛患者中性粒细胞氧化代谢与心律失常关系的研究
Assessment on the relationship of polymorphonuclear leukocyte metabolism and cardiac arrhythmia in angina pectoris patients
【摘要】 目的了解中性粒细胞氧化代谢在冠心病心绞痛患者心律失常发病中的作用。方法应用鲁米诺依赖的分离中性粒细胞化学发光法检测冠心病心绞痛尤其是合并心律失常者与窦性心律者中性粒细胞氧化代谢功能。结果冠心病心绞痛合并心律失常者与窦性心律者中性粒细胞化学发光峰值、积分均高于正常对照组,冠心病心绞痛合并心律失常组中性粒细胞化学发光峰值明显高于冠心病心绞痛窦性心律组。结论冠心病心绞痛合并心律失常者的发病与中性粒细胞氧化代谢有关。
【Abstract】 Objective to assess the efffects of polymorphonuclear leukocyte(PMN)metabolism on cardiac arrhy thmia in patients with angina pectoris(AP).Mathods Using luminol dependent separated PMN chemiluminescence(CL)techonology,PMN metabolism in AP patients with cardiac arrhythmias and those with sinus rhythm were studied.Results PMN-CL peak-value and its integration were higher in both AP patients acompanying cardiac arrhythmias and with sinus rhythm than that in normal subjects. PMN—CL peak-value in AP patients aeompanying cardiac arrhythmias was significantly higher than that in AP patients with sinus rhythm.Conclusion The onset of cardiac arrhythmias in patients with AP is re- levant to PMN metabolism.
【Key words】 Angina pectoris; Cardiac arrhythmia; Polymorphonuclear leukocyte; Oxygen free radical; Chemiluminescence;
- 【文献出处】 中华心律失常学杂志 ,Chinese Journal of Cardiac Arrhythmias , 编辑部邮箱 ,1998年01期
- 【分类号】R541.4;R541.7
- 【下载频次】17