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应用自体肺移植技术治疗Ⅲ期肺癌

Lung autotransplantation technique in the treatment of stage Ⅲ bronchogenic carcinoma

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【作者】 张国良李梦赞颜国义刘军姜冠潮

【Author】 Zhang Guoliang,Li Mengzan,Yan Guoyi,et al.Department of Thoracic Surgery,People′s Hospital,Beijing Medical University,Beijing 100044.

【机构】 北京医科大学人民医院胸外科

【摘要】 目的探讨应用下肺静脉移植于上肺静脉残端的方法行双袖状右上、中肺叶联合切除术治疗Ⅲ期肺癌的可行性。方法下肺离体后置于肝素溶液中,15分钟后将下肺静脉吻合于上叶静脉残端。再行支气管吻合和肺动脉吻合。静脉、支气管、动脉吻合分别耗时15、14、10分钟,肺动脉阻断时间3小时。术后辅助通气6小时。结果术后5天拔胸管,肺膨胀良好,患者下地活动。术后3周螺旋CT肺血管、气管重建显示重植肺血液灌注和回流良好,支气管通畅。术后随访6个月余,患者生活质量良好并恢复工作。结论当肿瘤累及总支气管或肺动脉的长度过长而不能完成双袖状联合肺叶切除后的吻合时,可以考虑将自体肺移植技术应用于肺癌手术中。

【Abstract】 Objective To perform a double sleeve right upper and middle bilobectomy with transposing the inferior pulmonary vein to the superior one stump in a lung cancer patient. Method The “cut down” lobe was immersed in heparin solution in vitro for 15 minutes.It took 15,14 and 10 minutes to finish the anastomosis of pulomonary vein,bronchus, and artery.The pulmonary artery was blocked for 3 hours.Postoperatively,the patient underwent ventilation for 6 hours. Result In the 5th day after operation,reimplanting lung inflated well,the chest tube was retreated,and the patient can walk around.The reconstruction of pulmonary vessles and airway was done by spiral CT,which demonstrated no stenoses of bronchi and the pulmonary blood perfused and returned very well 3 weeks after operation.Follow up more than 6 months showed the patient had a good quality of life and resamed his work. Conclusion It is indicated to apply the technique of lung autotransplantation for operation on the central bronchogenic carcinoma when the main bronchus or pulmonary artery involved by tumor is too long to perform the anastomosis in the double sleeve bilobectomy.

  • 【文献出处】 中华外科杂志 ,Chiese Journal of Surgery , 编辑部邮箱 ,1998年03期
  • 【分类号】R734.2
  • 【被引频次】16
  • 【下载频次】113
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