【摘要】 目的介绍肢端皮肤角化过度增生症10例的治疗体会,其中掌跖角化病9例,疣状表皮结构不良1例。方法采用病变皮肤切除皮肤移植术治疗,其中两例有深部组织外露和放射性溃疡选用皮瓣修复,其余行皮片移植。结果 10例均获满意效果,追踪观察8年以上,无复发,能保持接近正常的功能活动。结论手部以皮片效果最佳,足底应用皮瓣修复,耐磨性较皮片为好,但因皮瓣缺乏纤维隔结构,走路时皮瓣与深部组织间产生相对滑动,也容易造成破溃,必须注意妥为保护。更多还原

【Abstract】 Objective We introduce the experience of treating 10 cases with excessive hyperplasia of skin keratosis at the limb end.There were 9 cases of palmar and plantar keratosis and 1 case of epidermodysplasia verruciformis.Method All cases received the operation of lesion excision and skin grafting except 2 cases who received skin flap for defect covering after lesion excision because of deep tissue exposure and postradiation ulcer.Result The operative effects were satisfactory after 8 years of follow-up.No recurrence was found in all cases and all patients resumed normal activity.Con- clusion The effect of the skin flap is better than skin graft at the plantar area.Because of lack of fi- brous septum in the subcutaneous tissue,the flap,often moving during walking,is liable to trauma and ulceration.The operation area must be well protected.更多还原