【摘要】 目的:了解冠状动脉搭桥术围术期的氧合状态。方法:测定了55例采用咪唑安定、芬太尼和维库溴铵诱导,芬太尼及异氟醚维持麻醉接受冠状动脉搭桥术的病人诱导后、终止体外循环、术终和术后1日的心脏指数（CI）、氧转运（TO₂）、氧耗量（VO₂）、氧摄取率（O₂ER）以及血乳酸水平。结果:终止体外循环、术终和术后1日TO₂和VO₂之间存在着明显的相关关系（r分别为0.7817、0.559和0.7754,P<0.01）。其中测定了12例病人血中乳酸浓度显示,停机后乳酸显著升高（3.50±2.30mmol/L,P<0.05）。结论:冠脉搭桥术围术期呈现出氧耗的供给依赖性关系,冠脉搭桥手术结束时,氧耗量增加,术后1日仍处于高代谢状态。更多还原

【Abstract】 To investigate the perioperative oxygenation of the patient undergoing coronary artery bypass grafting procedure （CABG）. Method: The relationship between oxygen transport （TO₂） and oxygen consumption （VO₂）, and serum lactate level were examined in 55 patients undergoing CABF, anesthetized with midazolam, vecuronium and a moderate dose of fentanyl. Result: Good correlations between TO₂ and VO₂ at the weaning from CPB （r=0.7817, P<0.01）, the end of the procedure（r=0.5597, P<0.01）and one day post operation （r=0.7754, P<0.01） were shown respectively. Serum lactate level was higher （3.50±2.30 mmol/L, P<0.01） at the weaning from CPB than that at the end of the operation and one day post operation in 12 patients undergoing CABG. Conclusion: Oxygen supply-consumption dependency exists in the perioperative period of CABG. It is important for avoiding the inadequacy of tissue oxygenation to improve TO₂ during and after CPB, cspecially immediately weaning from CPB.更多还原