【摘要】 目的探讨影响精神分裂症病程和结局的相关因素。方法采用标准化的评定工具，对北京市四季青乡８２例精神分裂症进行现场调查和评定，并进行多元逐步回归分析和通径分析。结果（１）结局好的患者约占１／３，而２／３的病例结局不良；（２）影响结局的主要相关因素有：精神病发作次数，持续治疗，自杀行为，阴性症状，家属经济状况和总的疾病发展趋势；（３）６个主要相关因素之间存在相互作用。结论预防精神分裂症衰退结局的重点在于阻止精神分裂症日趋恶化的发展趋势，治疗和缓解精神分裂症的阴性症状。更多还原

【Abstract】 Objective The purpose of this study was to investigate the influential factors on the course and outcome of schizophrenia. Methods Eighty two schizophrenics in Sijiqing village, Haidian District, Beijing were investigated and evaluated using standard assessment instruments. The information collected from field investigation was analyzed by means of multivariate analyses of stepwise regression and path analysis. Results 1. About one third of these patients had a good outcome, but other two thirds didn′t; 2. The six main factors correlated to schizophrenic outcome included: numbers of psychotic episodes, duration of persistent treatment, suicide behavior, negative symptoms, economic status of the patients′ family and the trend of schizophrenic development over time; 3. Interaction existed in these six factors. Conclusion These findings suggest that the prevention of schizophrenic deterioration should be emphasized on the control of the increasing development trend over time and to relieve negative symptoms.更多还原