【摘要】 目的探讨局部脑血流（ｒＣＢＦ）断层显像对突发性感音神经性聋（简称突聋）的临床价值。方法对１０例正常志愿者，１９例传音性耳聋（简称传聋）及３１例突聋患者治疗前行ｒＣＢＦ显像，并与同期ＣＴ对照；随访突聋病例６～１２个月，并复查ｒＣＢＦ显像。结果①突聋的病灶（位于颞横回）与正常脑组织的放射性比值（Ｔ／ＮＴ）明显低于传聋和正常组；②ｒＣＢＦ显像诊断突聋的灵敏度（８０６％）和准确率（８８３％）明显高于ＣＴ（３２％和５０％）；③突聋的Ｔ／ＮＴ值与耳聋程度有较高的相关性；④ｒＣＢＦ显像无异常的突聋患者预后较好；⑤ｒＣＢＦ显像与临床预后观察有较高的一致性（８４６％）。结论ｒＣＢＦ显像对突聋的诊断明显优于ＣＴ。更多还原

【Abstract】 Purpose To study the clinical value of regional cerebral blood flow (rCBF) SPECT imaging for sudden sensorineural deafness (SSD) Methods 10 normal persons, 19 conductive deafness and 31 SSD patients were examined by rCBF SPECT imaging, and compared with X CT at the same time All SSD patients were followed up for 6～12 months with repeated rCBF SPECT imaging Results ①The radioactivity of diseased and normal horizontal temporal gyrus ratio (T/NT) in SSD patients was the lowest among three groups (P<0 01) ②The sensitivity (80 6%) and accurate rate (88 3%) of rCBF SPECT imaging in SSD patients were much higher than those of CT (3 2% and 50%, P<0 01) ③There was a significant correlation between degree of deafness and T/NT in SSD patients ④Good prognosis of SSD patients with normal rCBF SPECT was found ⑤The rCBF SPECT had close concordance between rCBF SPECT imaging and clinical prognosis (84 6%) Conclusions rCBF SPECT imaging was superior to X CT in diagnosis of SSD and played an important clinical role更多还原