Ischemia is one of the most important mechanisms of secondary spinal cord injury (SCI).Endothelin (ET) is the most potent and long-lasting vasoconstrictive peptide,which is expressed in the central nervous system and may act as a neuromodulator.ET has been proved to play an important role in some cerebral vascular diseases,and there were also experimental evidence indicating the possible relationship between ET and SCI.In this study,the ET level in both spinal cord and plasma was measured after an acute exp...