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Studies on ~1H-NMR of Naturally Occuring Taxane Diterpenoids and Revising Suggestions on Some Structures

Studies on 1H NMR of Naturally Occurring Taxane Diterpenoids and Revising Suggestions on Some Structures

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【作者】 黄开胜; 梁敬钰;

【Author】 Huang Kaisheng 1, Liang Jingyu and A A Leslie Gunatilaka 2 Department of phytochemistry,China Pharmaceutical University Nanjing 210009; 2Bioresources Research Facility, Office of Arid Lands Studies, University of Arizona, 250E Valencia Road, Tucs

【机构】 中国药科大学植化教研室;

【摘要】 本文对已经报道的天然紫杉烷类化合物按照一种新的方法进行分类,并在此基础上研究了这类化合物的氢谱。研究发现Ⅰ类骨架(6/8/6环系统)和Ⅱ类骨架(5/7/6环系统)的化合物在氢谱上有明显的区别,而且有些Ⅱ类骨架的化合物被误定为Ⅰ类骨架。根据氢谱的研究,对误定的一些化合物提出了修改的建议,这些修改建议得到了碳谱数据的支持

【Abstract】 More than 200 taxoids were isolated from genus Taxus,and their structures were elucidated mainly by spectroscopic means, especially on the basis of 1H NMR data′ analysis We try to group all of the taxoids by a new means and discuss their 1H NMR features in detail Based on the discussion, some structures revising suggestions were put forth for the structures which can not accord with their 1H NMR data properly

  • 【文献出处】 中国药科大学学报 ,JOURNAL OF CHINA PHARMACEUTICAL UNIVERSITY , 编辑部邮箱 ,1998年04期
  • 【分类号】TQ461,R285.1
  • 【被引频次】7
  • 【下载频次】55
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