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益气活血化瘀汤用药剂量与药效关系的探讨

Study on the Relationship Between the Dosage and Drug Effect of Yiqi Huoxue Huayu Decoction

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【作者】 魏凤玲高惠玲钟加胜

【Author】 WEI Fengling; GAO Huiling; ZHONG Jiasheng (Beijing Sino-Japen Friendship Hospital,Beijing 100029)

【机构】 中日友好医院!北京市100029

【摘要】 用含Adine饲料产生肾功能衰竭状态的大鼠模型,通过大黄、丹参、黄芪、桂枝组成的益气活血化瘀方对肾功能的改善作用研究,对用药剂量与药效关系进行了探讨。结果表明,给药量过低、过高时,对肾功能的改善作用均不明显。

【Abstract】 Yiqi Huoxue Huayu decoction is composed of rhubarb,red sage root,astragalus root and cassia twig,and has the effect of promoting blood circulation and removing blood stasis.Taken renal failure rats,induced by feeding "Adine" food,as model,the relationship between the dosage and drug effect of this decoction was investigated,The results showed that a distinct improvement of rat’s renal function was obtained in an appropriated dosage of this decoction,and no obvious effect could be found in lower or higher dosages.

【关键词】 中药剂量药效
【Key words】 traditional Chinese drugs dosage drug effect
  • 【分类号】R285
  • 【下载频次】76
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