【摘要】 目的探讨小睑裂综合征的临床特点，手术效果及遗传学研究进展。方法回顾性分析我院１９９２年１１月至１９９７年３月间收治的小睑裂综合征１６例。结果其中４例同时行内外眦开大和上睑下垂矫正术，１２例先行内外眦开大术，２周或３个月后行上睑下垂矫正术；７例有完整的散瞳验光结果，６例双眼有不同程度的弱视；随访时间３个月～５年４个月。结论小睑裂综合征病人屈光不正和弱视的发生率远高于正常人群，应尽早手术治疗，然而术后功能及美容效果尚不满意更多还原

【Abstract】 Abstract Objective To evaluate the clinical characteristics, surgical results and the genetic progress of blepharophimosis-ptosis-epicanthus inversus syndrome (BPES).Method 16 cases of BPES were retrospectively reviewed from November 1992 to March 1997.Results In the follow-up periods ranged from 3 months to 5 years and 4 months, all of 16 cases treated by surgical. The stage 1 technique was used to correct the epicanthus inversus, telecanthus and ptosis in 4 cases, the stage 2 technique was to used to treat 12 cases for correction of epicanthus inversus first and then the ptosis operation after 2 weeks or 3 months. 7 cases had cycloplegic refraction and 6 cases were found to have bilateral amblyopia with different severity. Conclusion The incidence of refractive error and amblyopia in patients with BPES is higher than normal population, they need approppriate early surgery, but up to now the functional and cosmetic results are not satisfied.更多还原