【摘要】 目的:探讨前列腺内局限性弱回声灶与PSAD的关系,以提高对前列腺癌的早期检出率。方法:采用直肠超声法。结果:检出前列腺弱回声灶65例,范围0.5～2.0cm~2,84.61％位于移行区。病检证实前列腺癌(PCa)35例(53.84％),前列腺上皮内瘤(PIN)13例(20％),结节增生17例(26.15％)。以PSA10ng/ml和PSAD0.1为界值,对PCa和PIN的敏感性是52％和85％,特异性90％和56％,阳性预测值90％和71％。结论:前列腺弱回声灶和PSAD较单一指标能提高对前列腺癌的检出率。更多还原

【Abstract】 Objective: For to elevate the early diagnostic rate the relation between prostatic hypoechoic foci, PSAD and prostatic cancer was studied. Methods:65 prostatic hyoechoic foci found by TRUS,serum PSA level detected and PSAD calculated.Results:The size of these foci ranged 0.5～2.0cm~2, and 84.61％ were located in transitional zone. 35 cases(53.84％) of all with hypoechoic foci were P.ca confirmed by pathological examination,in which 13 cases(20％)were PIN and 17(26.15％) were AAH. Compared with the upper limit of PSA level<10ng/ml and PSAD 0.1. The sensitivity of P.ca and PIN were 52％ and 85％ respectively,the specificity were 90％ and 56％ respectively and the positive predictive value were 90％ and 71％ respectively.Conclusion: Hypoechoic foci may enhance the defective rate of prostatic cancer.更多还原