【摘要】 目的:探讨门静脉循环r照相诊断肝硬化,特别是代偿期肝硬化的价值。材料与方法:用^99mTcO4^-直肠给药法进行门静脉循环r照相,计算门脉分流指数（SI）,并与B超、CT、胃镜等进行比较。结果:肝心循环时间和SI均值正常人分别为21.6±2.4sec和7.1±2.3％,慢性肝炎分别为18.6±5.7sec和10.7±3.1％,代偿期肝硬化分别为12.6±3.7sec和20.8±4.5％,失代偿期肝硬化分别为-35±25sec和68.2+20.7％,若以慢性肝炎SI均值+2SD即16.9％作判别阈,肝硬化患者阳性率为90.6％,特异性100％,准确性93.6％。单代偿期肝硬化阳性率亦达85％,特异性100％,准确率94.1％,比上述其他检查方法为优。结论:SI测定是安全、简便、准确的早期诊断肝硬化技术,适合临床推广应用。更多还原

【Abstract】 Purpose: To evaluate the efficacy of portal circulation rimaging in diagnosing liver cirrhosis, especially in the compensted stage. Materials and Methods; Portal circulation imaging was performed per - rectal 99mTcO4- and calculation of portal shunt index (SI). Comparison was made with B - mode ultrasound, CT and gastroscopy. Results; Liver- heart circulation time and SI values of normal subjects were 21.6 ±2.4sec and 7.1 + 2.3% respectively, of chronic hepatitis were 18. 6 ± 5. 7sec and 10. 7 ± 3. 1%, of. compensated cirrhosis were 12. 6 ± 3. 7sec and 20. 8 ± 4. 5% , and decompensated cirrhosis were - 35 ±25sec and 68.2 ±20.7%. If the threshold for cirrhosis was set at the mean of chronic hepatitis + 2SD, namely 16.9% , the sensitivity was 90.6% , specificity 100% , and accuracy 93.6%. If compensated cirrhosis alone was dealt with, the sensitivity was 85% , speciticity 100% and accurracy 94.1%. Thus, SI was superior to the above other methods. Conclusions: Portal shunt index determination was a safe, convenient and accurate method for the early diagnosis of cirrhosis, suitable for widespread clinical application.更多还原