【摘要】 应用免疫酶法及ＰＣＲ同时检测４２例ＮＰＣ患者及１３例头颈部其它肿瘤患者的ＥＢ病毒。结果ＮＰＣ患者血清ＩｇＡ／ＶＣＡ、ＩｇＡ／ＥＡ抗体滴度较高，其阳性率分别为７３．８％（３１／４２）、７１．４％（３０／４２），两者比较差异无显著性（Ｐ＞０．０５），而ＰＣＲ检测的阳性率高达９７．６％（４１／４２），与免疫酶法比较差异有高度显著性（Ｐ＜０．０１）。表明ＰＣＲ技术有极高的灵敏度和较强的特异性。其阳性检出率高于沿用的免疫酶法更多还原

【Abstract】 EB viruses in 42 patients with nasopharygeal carcinoma (NPC) and 13 patients with other neoplasms in head and neck had been detected by applying immnoenzyme method and PCR at the same time. Results showed that the serum in NPC patients had higher IgA/VCA and IgA/EA antibody titers, their positive rates were 73.8 percent(31/42) and 71.4 percent (30/42), respectively, no significant difference between the two (P>0.05), but the positive rate reached to 97.6 percent (41/41) in PCR detection. So it indicated that PCR had high sensitivity and strong specificity and its positive detectable rate is higher than the continued use immunenzyne.更多还原