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结核性和癌性胸水中NO水平测定

STUDY OF THE LEVELS OF NO IN PLEURAL FLUID WITH TUBERCULOSIS AND LUNG CANCER

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【作者】 王晓铃; 张玲; 胡觉文;

【Author】 Wang Xiaoling;et al.

【机构】 扬州大学医学院附属医院!扬州; 225001;

【摘要】 用酶法检测结核性和非结核性胸水及血清中NO含量,结果显示.结核组NO水平明显升高(15±43μmol/l,)与癌性胸水组比有明显性差异(P<0.01)。结核性胸水NO含量与SIL-2R呈正相关(r=0.654,P<0.01),敏感性(97%)、特异性(82%)均较理想。测定购水中NO,对于结核性胸水诊断、鉴别诊断和病因学研究有一定意义。

【Abstract】 The levels of NO were determined in pleural fluid and serum from 24 patients with tuberculous pleurisy and 49 nontuberculous (28 cases of malignant, 2l cases of transudative). There were significantly elevated NO values in tuberculous pleural fluid as compared with malignant effusi0n. A significantpositive correlation was observed between NO levels and IL-2R levels in tubercul0us pleural fluid (Y =0.654, P <0.01)- Fixing the cut off point of NO values at l5OUmol/L the tuberculous pleural effusi0n caseswere differentiated from the nontuberculous with a sensitivity, specificity value and accuracy 0f over 80 percent.

【关键词】 一氧化氮; 结核; 胸膜; 肺肿瘤; 胸腔积液;
【Key words】 NO; tuberculosis, pleural; lung neoplasms; pleural effusion;
  • 【文献出处】 江苏临床医学杂志 ,JOURNAL OF JIANGSU CLINICAL MEDICINE , 编辑部邮箱 ,1998年03期
  • 【分类号】R730.4
  • 【下载频次】11
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