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大鼠离体心脏缺血再灌时冠脉流出液中肌钙蛋白T比较观察

Comparison between Troponin T and Cardiac Enzymes in Coronary Effluent from Isolated Rat Hearts during Reperfusion

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【作者】 王建璞王军蒋建渝

【Author】 Wang Jianpu; Wang Jun; Jiang Jianyu.(Department of Anesthesiology, the Third Teaching Hospital Beijing Medical University. Beijing 100083)

【机构】 河北省唐山市华北煤炭医学院附属医院麻醉科!100083北京医科大学第三临床医学院麻醉科!100083

【摘要】 在观察腺苷心脏停搏液的心肌保护效果时,应用酶联免疫吸附测定法对大鼠离休心脏冠脉流出液中的心脏肌钙蛋白T(TnT)进行检测,同时与心肌漏出酶(LDHCK)进行了检测比较。结果表明:1.TnT用于检测离体心脏心肌损伤程度可能比LDH和CK更敏感。2.TnT与LDH或CK相关性很好(r=0.901,r=0.869),LDH和CK相关性也很好(r=0.967)。

【Abstract】 Troponin T(TnT) in coronary effluent from isolated rat hearts were detected using the enzyme-linked immuno-sorbent assay during the study of myocadial protective effects of adenosine cardioplegia. Cardiac enzymes(LDH, CK) levels were compared with that of TnT. These studies indicated that (1) the measurements of TnT might be more sensitive for the detection of myocardial damage in the isolated rat heaxts than that of LDH and CK and (2) there were strong correlation between TnT and LDH (r=0.901) or CK(r=0.869). Also, there was very close relationship between LDH and CK (r=0.967).

【关键词】 肌钙蛋白T心肌损伤离体鼠心
【Key words】 Troponin TMyocardial damageIsolatad rat heart
  • 【文献出处】 心肺血管病杂志 ,JOURNAL OF CARDIOVASCULAR AND PULMONARY DISEASES , 编辑部邮箱 ,1998年01期
  • 【分类号】R542.22
  • 【被引频次】5
  • 【下载频次】34
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