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吸附霍乱菌苗免疫后人群血清杀弧菌抗体观察

The Observation of Serum Vibriocidal Antibody of Cholera

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【作者】 曾令冰鲁涛黄佐林汪玉兰蒋玉亭丁兆松

【Author】 Zeng Lingbing et al.(Wuhan Institute of Biological Products,Wuchang 430060)

【机构】 卫生部武汉生物制品研究所

【摘要】 本文介绍了用霍乱杀弧菌抗体微量法,检测经O1型吸附霍乱菌苗免疫前后人群的O1型霍乱和O139型霍乱的血清杀弧菌抗体。结果表明,免前人群的Inaba、Ogawa、O139型三种自然杀弧菌抗体很低(GMT在5.49以下),免后Inaba和Ogawa型杀弧菌抗体大幅度增加,GMT分别达到782和592、O139型霍乱杀弧菌抗体免疫前后无变化

【Abstract】 Test of serum vibriocidal antibody of preimmunization and postimmunization with absorbed cholera vaccine was done with microplate method.The results Showed that nature serum vibriocidel antibody of Inaba,Ogawa and O139 of preimmunization was quite low but the increase rate of vibriocidal antibody of Inaba and Ogawa was high afer immunization with absorbed Cholera vaccine.Geomtry mean titer (GMT) reached 782 and 592,respectively.There was no change about vibriocidal antibody of O139 Cholera either in preimmunization or in postimmunization.This method was rapid and accurate.The doses of serum needed was small.The resulte were easy to observe.

【关键词】 霍乱杀弧菌抗体免疫
【Key words】 Cholera Vibriocidal Autibody Immune
  • 【文献出处】 微生物学免疫学进展 ,PROGRESS IN MICROBIOLOGY AND IMMUNOLOGY , 编辑部邮箱 ,1998年03期
  • 【分类号】R516.5
  • 【被引频次】1
  • 【下载频次】22
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