【摘要】 目的探讨糖尿病（ＤＭ）患者运动神经中枢及神经根、周围神经的功能。方法应用经皮质、脊髓电刺激运动诱发电位（ＭＥＰ）对５０例ＤＭ患者进行观察。结果ＤＭ组异常率８２％（４１／５０）；表现为皮质、脊髓刺激ＭＥＰ潜伏期延迟、波形分化欠佳，部分伴有中枢传导时间（ＣＭＣＴ）异常。ＭＥＰ异常率与病程长短呈正相关；空腹血糖水平对ＭＥＰ结果无明显影响。结论ＤＭ患者的锥体束及神经根、周围神经功能均存在明显异常。ＭＥＰ结合神经电图（ＥＮＧ）、体感诱发电位（ＳＥＰ）等可对ＤＭ的神经系统功能提供全面客观指标更多还原

【Abstract】 Objectives To study the function of motor nerve center,nerve root and peripheral nerve in patients with diabetes mellitus (DM). Methods Motor evoked potentials (MEP) by electrostimulation in cerebral cortex and spinal cord were performed in 50 patients with DM. Results The abnormal rate of MEP was 82% (41/50).The main changes were the prolonged latency and unclear waveform.Central motor conduction time (CMCT) were prolonged in six patients.There was significant correlation between the course of disease and the abnormal rate of MEP;There was no significant relation between the result of MEP and the level of fasting blood sugar. Conclusions The MEP revealed that abnormality of pyramidal tract,nerve root and peripheral nerve may occur in patients with DM.The examination of MEP combined with ENG SEP may provide objective index for function of nerve system in patients with DM.更多还原