【摘要】 本文研究置消炎痛铜珠宫内节育器3～6月后对防治带器出血的子宫内膜形态学观察.结果显示子宫内膜的增殖活性、炎性细胞反应、因子Ⅷ活性无明显差异(P>0.05).含消炎痛铜珠节育器可减少植入后因多形核白细胞、噬细胞增多,而纤溶活性增强的出血,并可调控血管功能而有助于置器后减少出血作用.更多还原

【Abstract】 In the present study,we investigated the endometrial change after insertion of indomethac in-releasing copper intrauterine device (IR -Cu -IUD) 3~6 months. Endometrial morphology, cell proliferation,inflammatory reaction and activity of complement Factor VI were examined. No sig-nificant difference was found (P>0. 05) in all the parameters examined in the same patients prior and after IR - Cu - IUD insertion. But comparing the data previously obtained from the patients with Cu -IUD insertion.it is clear that the amount of uterine bleeding after insertion of IR -Cu -IUD is much less. We suggest that the reduction of bleeding primarily contributes to the anti -in-flammatory action and reduction of fibrinolysis of indomethacin, which controls the function of vessels and helps to stop bleeding after insertion.更多还原