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诺氟沙星与维生素C的配伍实验
The Compatibility Test of Norfloxacin and Vitamin C
【摘要】 经实验:诺氟沙星和维生素C注射液在25℃0—4h内。经UV—1601紫外/可见分光光度的测定吸收峰/谷、曲线均发生改变,pH值变化不大,但澄明度检查,微粒增多,说明二药合用有物理、化学变化发生。据推算4h内诺氟沙星的含量下降了19%以上。二药混合配伍属于不合理用药。
【Abstract】 After determination by UV - 1601 SpL-cuoplometry, we found that the peak -ABS. val’v ? ABS and the carve of commixture of Norfloxacin injection and Vitamin C injection had changed at 25 C , in 4h. This illustrates both two drugs had changed in physics and chemistry, they can not be used in combination with each other.
【关键词】 诺氟沙星;
维生素C;
配伍实验;
UV;
1601;
【Key words】 N’orfloxacin; Vitamin C; Compatibility lest; LiV 1601 Spectroptometry;
【Key words】 N’orfloxacin; Vitamin C; Compatibility lest; LiV 1601 Spectroptometry;
- 【文献出处】 实用医技杂志 ,Journal of Practical Medical Techniques , 编辑部邮箱 ,1998年02期
- 【分类号】R942
- 【下载频次】23