【摘要】 目的了解经皮二尖瓣球囊扩张术（ＰＢＭＶ）近期血流动力学改变规律和相互关系，从而指导ＰＢＭＶ操作的改进。方法对５５例二尖瓣狭窄患者，于术前、术后１周内均行超声心动图检查测量二尖瓣口面积（ＭＶＡ）、左房内径（ＬＡＤ）和肺动脉平均压（ＰＡＰ多谱勒法），术中常规检测扩张前后的左房平均压（ＬＡＰ）和肺动脉平均压（ＰＡＰ导管法）。结果ＰＢＭＶ术后，ＭＶＡ显著增加（Ｐ＜０．０５），增加幅度为（０．６８±０．３１）ｃｍ２，增加率为（６９．３±４０．７）％；ＬＡＰ显著降低（Ｐ＜０．０５），降低幅度为（３７．５±１６．８）％；ＰＡＰ（导管法）、ＰＡＰ（多普勒法）、ＬＡＤ与术前相比差别无显著性。相关分析可知，ΔＭＶＡ和ΔＬＡＰ存在相关关系；导管法、多普勒法测定的ＰＡＰ之间也存在相关关系。结论由术中ΔＬＡＰ可推断ΔＭＶＡ，ΔＬＡＰ可反映ＰＢＭＶ的效果。本研究结果中使ＰＢＭＶ效果的判断更简便，具有临床实用价值。更多还原

【Abstract】 URPOSE To find out some ragularity and relationship in the hemodynamics shortly after percutaneous balloon mitral valvoplasty (PBMV).METHODS 55 cases of mitral stenosis (MS) were studied who were performed PBMV successively in our hospital from Jan. 1995 to Jun. 1997, male 13, female 42, age ranged 11～65 years old. Mitral valve area (MVA), left atrium diameter (LAD), mean pulmonary artery pressure (PAP-Dopplar) were detected echocardiographically before PBMV and within a week after PBMV. Mean left atrium pressure (LAP) and mean PAP-duct were also measured before and after dilatation of mitral valve during PBMV.RESULTS MVA increased significantly (P<0.05), ΔMVA (0.68±0.31)cm2, increased proportion (69.3±40.7)%; LAP reduced significantly (P<0.05), the reduced proportion was (37.5±16.8)%; differences between before and after operation in PAP-Dopplar, PAP-duct and LAD were not significant. Correlation existed in ΔMVA and ΔLAP, also in PAP-Dopplar and PAP-duct.CONCLUSIONS ΔMVA can be deduced from ΔLAP, ΔLAP can reflect the effect of PBMV, PBMV can be simplified.更多还原