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银环蛇血清中神经解毒因子的研究
Purification of a Antineurotoxic Factor from Serum of Snake Bungarus multicinctus
【摘要】 银环蛇血清中神经解毒因子的研究*沈燕琴邵靖宇**(浙江医科大学生物化学教研室,杭州310031)关键词β-BuTx;神经解毒因子;银环蛇;磷脂酶A2银环蛇与眼镜蛇同属眼镜蛇科眼镜蛇亚科而不同属的一种剧毒蛇,其毒液中含有两类作用机制和作用部位不同的神经...
【Abstract】 An ntineurotoxic factor has been purified from the serum of the snake B.multicinctus. The purified antineurotoxic factor shows a single band in PAGE and SDSPAGE, running in the region of α2 or βglobulin. This antineurotoxic factor is a glycoprotein and its molecular weight is (80±5) kD, This antineurotoxic factor can partially neutralize the toxicity of βBuTx and possesses inbibition activity to the βBuTx PLA2 enzyme.
【关键词】 β-BuTx;
神经解毒因子;
银环蛇;
磷脂酶A2;
【Key words】 βBuTx; antineurotoxic factor; B.multicinctus; phospholipase A2;
【Key words】 βBuTx; antineurotoxic factor; B.multicinctus; phospholipase A2;
【基金】 国家自然科学基金
- 【文献出处】 生物化学与生物物理学报 ,ACTA BIOCHIMICA ET BIOPHYSICA SINICA , 编辑部邮箱 ,1998年04期
- 【分类号】Q55,
- 【被引频次】2
- 【下载频次】82