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肌萎缩侧索硬化低频电刺激时波幅的衰减

DECREMENT OF AMPLITUDE TO REPETITIVE NERVE STIMULATION AT SLOW RATES IN AMYOTROPHIC LATERAL SCLEROSIS

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【作者】 张为西吕建敏

【Author】 Zhang Weixi,Lu JianminDepartment of neurology,First Affiliated Hospital,Sun Yat-sen University of Medical Sciences,Guangzhou,510080

【机构】 中山医科大学附属第一医院神经科中山医科大学附属第一医院神经科 510080510080

【摘要】 目的:为了探讨肌萎缩侧索硬化低频重复电刺激时波幅的变化。方法:运用丹麦丹迪公司生产的Countpoint肌电图机对30例肌萎缩侧索硬化患者及30例正常人进行低频重复电刺激的研究。结果:半数以上的患者波幅呈递减反应,波幅的衰减在有束颤及肌萎缩者明显,动作电位的低波幅与波幅的衰减率是呈相关。结论:肌萎缩侧索硬化存在神经肌肉接头损害。

【Abstract】 Objective:to explore the change of amplitude to repetitive nerve stimulation (RNS) at slow rates in amyotrophic lateral sclerosis (ALS).Methods:30 patients with ALS and 30 normal volunteers were given RNS test at slow rates by electromyography made in Dantec of demark.Results:at least half of patients with ALS had some degree of decrement of amplitude to RNS.Decremental responses are apparent in the patients with muscular alrophy and fasciculation.There was a negative correlation between lower amplitude and decrement of amplitude.Conclusions:there is functional alteration of neuromuscular junction in ALS.

【关键词】 肌萎缩侧索硬化重复电刺激
【Key words】 ALSRNS
  • 【分类号】R746.4
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