【摘要】 目的了解肥厚型心肌病遗传规律；探讨彩色多普勒心肌组织显像（DTI）对该病的诊断价值。方法采用家系调查。对肥厚型心肌病人用DTI测定左室后壁及室间隔厚度，测定二尖辩环、左室后壁、心尖部及空间隔运动速度。结果该家系4代68人确诊为肥厚型心肌病8例，其中梗阻性3例，非梗阻性5例。心肌舒张功能指标：MVRDEV、LVPWENDV、LVPWEXDV、LVPWMDV、APMDV显著降低，反映收缩功能指标部分降低。结论肥厚型心肌病符合常染色体显性遗传。DTI对该病的诊断及了解心脏功能都具有重要价值。更多还原

【Abstract】 Objective in order to investigate the hereditary law and diagnostic value of colorDoppler tissue imaging (DTI) in patients with hypertrophic cardiomyopathy. Methods The family investigation were carried out. The thickness of left ventricular posticus wall and ventricular septum, thespeeds in motion of mitral ring, left ventricular postcus wall, apex and ventricular septum were measured by DTI in patients with hypertrophic cardiomyopathy. Results of 68 members of 4 generationsof this family. 8 cases with hypertrophic cardiomyopathy were diagnosed, including 3 obstractive casesand 5 non-obstractive ones. The myocardial diastolic indices (MVRDEV LVPWENDV LVPWEXDVLVPWMDV APMDV) were decreased markedly and the myocardial systolic indices were partly reduced. Conclusion Hypertrophic cardiomyopathy belongs in autosomal heredity. DTI may be an important method in diagnosis of patients with hypertrophic cardiomyopathy.更多还原