【摘要】 目的探讨恶性肿瘤外周血T淋巴细胞亚群的表达及其临床意义。方法应用酶免染色技术对50例恶性肿瘤患者外周血T淋巴细胞亚群进行测定，并与50例健康人T淋巴细胞亚群的含量进行了比较分析。结果恶性肿瘤患者CD下降（P＜0．01），CD8升高（P＜0．01），CD4／CD8比值下降（P＜0．01）。结论提示恶性肿瘤患者免疫平衡失调，细胞免疫功能下降。更多还原

【Abstract】 Objectives To educidate the expression of T Lpophocyte subpopulation in peripheral blood of malignant Carcinoma and Its clini-cal implication. Methods Amount of T lymphocyte subpopulations in peripheral blood were assayed in 50 patients with malignant car-cinoma and in 50 normal subjects by using enzymoimmunostaining. Results The level of CD3 was lower in patients group than in nor-mal controls (P <0. 01 )and the level of CD8 was higher in patients than in normal contros (P < 0. 01). the ratio of CD4/CD8 was lower in patients than in normal controls (P < 0. 01). Conclusion Suggest that there are disturbance of immunologic balance and de-crease of cellular mediated immunity in the patients with malignant carcinoma.更多还原