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包皮中人乳头瘤病毒的感染及意义

The significance of human papillomavirus infection in foreskin

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【作者】 马胜利; 胡礼泉; 郑新民; 鲁德根;

【Author】 Ma Shengli; Hu Liquan;Zheng Xinmin et al(Department of Urology, The Second Affiniated Hospital of Hubei Medical University Wuhan, 430071 )

【机构】 湖北医科大学附属二医院泌尿外科!武汉; 430071; 湖北医科大学病毒研究所;

【摘要】 目的和方法:人孔头瘤病毒16、18型感染与宫颈癌及阴茎癌的发生有密切关系,从预防角度出发,我们采用PCR-DNA扩增的方法,检测了48例包皮环切标本中HPV6,11,16,18,33型的DNA保守片段。结果:20例阳性,阳性率为41.7%。按年龄、有无包皮垢及有无感染史分组,各组间均无显著性差异。结论:主张男孩应尽早行包皮环切术。

【Abstract】 Objectives:Data suggest a ceratin relationship between carcinomas of the penis and the cervix uteri and Human papillomavirus infection. From the point of prevention of the development of penile caucinoma,we detected the infection of human papillomaviruses in foreskin,the polymerase chain reaction method was used. Results:The positive rate was 41. 7 % (20/48). There was no significant difference according to the age and the presence of smegma or the history of balanoposthitis. Conclusions: This result suggested that boys have to take the circumcision as early as possible.

  • 【分类号】R730.2
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