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三叉神经痛伽玛刀治疗(附30例分析)

Camma knife radiosurgery for treatmeat of trigeminal neuralgia

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【作者】 郑立高徐德生张丽茵张志远张宜培李彦和

【Author】 Zheng Ligao, Xu Desheng, Zhang Liyin, et al Gamma knife center 2nd Hospital Tianjin Medical University, Tianjin, 300211

【机构】 天津医科大学第二医院神经外科、伽玛刀中心

【摘要】 目的:介绍伽玛刀治疗三叉神经痛30例。方法:采用1.5TMR影像、Gamma-Plan定位和治疗计划,γ-刀(LEKSELL)治疗。治疗靶点在三叉神经感觉根桥脑进入区,用4mm准直器,最大剂量72~80Gy,50%等剂量线限定靶点;颅底肿瘤12~15Gy治疗。结果:随访3~24个月。疼痛100%缓解占60%,疼痛缓解>90%占23.3%,疼痛缓解>50%占6.33%,总有效率89.7%,2例无效,1例5个月后复发。无效和复发病人经再次治疗后疼痛100%缓解。全组病人无任何并发症。结论:伽玛刀是治疗三叉神经痛一种安全和有效的方法

【Abstract】 Objective: To introduce 30 cases Gamma knife radiosurgery for treatmeat of trigeminal neuralgia Methods: Localization and plan of treatmeat were made by 1 5T MRI images and Gamma plan dose planning system, LEKSELL Gamma knife was used treatmeat Target was localized in the sensory root of trigeminnal nerve entry zone of pons A single 4mm collimator helmet with maximal dose 72~80Gy was used, 50% isodose curve limited target Trigeminal neuralgia related to skull based tumor underwent treatmeat with 12~15Gy Results: The follow up ranged from 3 to 24 months 60% patients were completely pain relief (100% pain relief), 23 3% patients were pain relief more than 90% and 6 33% patients were pain relief more than 50% The overall effective rate was 89 7% In 2 patients (6 33%) the nenuralgia was unchanged 1 patients (3 33%) experienced recurrent pain at 5 months after pain relief, but these 4 patients were completely pain relief (100% pain relief) after second treatmeat by Gamma knife radiosurgery No complication occured in all of the patients Conclusions: Gamma knife radiosurgery for treatmeat of trigeminal neuraligia was a safety and effective method

  • 【文献出处】 立体定向和功能性神经外科杂志 ,CHINESE JOURNAL OF STEREOTACTIC AND FUNCTIONAL NEUROSURGERY , 编辑部邮箱 ,1998年04期
  • 【分类号】R651.3,R745.110.5
  • 【被引频次】5
  • 【下载频次】26
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