【摘要】 目的观察国产卡托普利注射液对扩张型心肌病（DCM）的急性血流动力学影响。方法选住院确诊DCM患者6例，采用自身对照的方法，于静脉给予卡托普利后30min及2hr，经Swan－Ganz导管测定平均肺动脉压（MPAP）、肺毛细血管楔嵌压（PCWP）、心输出量（CO）和心脏指数（CI）。结果卡托普利静脉注射可使MPAP及PCWP下降，而CO及CI增加，且用药后2hr较30min更为明显。结论国产卡托普利注射液对DCM患者具有良好的急性血流动力学效果。更多还原

【Abstract】 Objective To investigate acute hemodynamic effect of captopril intravenously administrated on patients with dilated cardiomyopathy (DCM). Methods For six patients with DCM the mean pulmonary artery pressure (MPAP), pulmonary capillary wedge pressure (PCWP), cardiac output (CO) and cardiac index (CI) were analyzed at both 30 min and two hr after intravenous administration of captopril using Swan-Ganz catheter. Results Both the increase of CO、CI and decrease of MPAP and PCWP were observed at 30 min and two hr after administration of the drug. This effect was more significant at two hr than at 30 min. Conclusion The intravenous administration of captopril could improve the hemodynamics in patients with DCM.更多还原