【摘要】 采用病例对照研究，对11年上海地区27家医院2867例急性白血病（AL）住院患者早期死亡的高危同素进行Lognistic回归分析。结果：出血、感染和多脏器衰竭是AL死亡的主要原因。全反式维甲酸（ATRA）的应用，降低了急性早幼粒细胞白血病（APL）早期病死率。早期死亡的高危因素为：年龄≥60岁或≤1岁，发病时伴有明显出血、外用血白细胞＞100X109／L、BPC＜50X109／L。结论：针对上述高危因素采取相应防治措施，降低AL的早期病死率十分必要。更多还原

【Abstract】 In order to know high risk factors of early death of acute leukemia (AL),the total of 2 867 cases with AL were collected from 27 hospitals in Shanghai area,Case-control study were used for design. Logistic regression were used to analyze the risk factors. The early death rates of AL within 30 days were 12%. The rates were higher in elderly patients and children(age of less that of 1 year old),Bleeding,infection and multiple organs failure were the main causes of early death- The high risk factors for early death within 30 days were the age of more than 60 years old or less than 1 year old, bleeding, DIC, enlargement of liver, peripheral WBC> 100 X109/L, BPC< 50 X 109/L, fever infection and AML更多还原