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苯那普利对高血压胰岛素抵抗和左室肥厚的影响
The effect of benazepril on insulin resistance and left ventricular hypertropy in patients with essential hypertension
【摘要】 应用苯那普利治疗原发性高血压患者30例,剂量为3~10mg/d,疗程24周,血压从治疗前24.3/14.4kPa降至18.6/10.5kPa;治疗后的血胰岛素水平、血胰岛素/葡萄糖比值和左心室重量均较治疗前下降(均P<0.05),提示:苯那普利有明显的改善胰岛素抵抗和左心室肥厚效应。
【Abstract】 Thirty patients with essential hypertension were treated with benazepril 3-10 mg daily for 24 weeks. The results showed that there were significant difference(P <0.05) in blood pressure(24. 3/14.4 kPa vs 18. 6/10. 5 kPa),Plasma insulin level,plasma insulin/glucose ratio and left ventricular hypertropy pre-and post-treatment. It suggests that benazepril has a obvious effect on improving insulin resistance and left ventricular hypertropy in patients with essential hypertension.
【关键词】 苯那普利;
高血压病;
胰岛素抵抗;
左心室肥厚;
【Key words】 Benazepril Essential hypertension Insulin resistance Left ventricular hypertropy;
【Key words】 Benazepril Essential hypertension Insulin resistance Left ventricular hypertropy;
- 【文献出处】 临床心血管病杂志 ,JOURNAL OF CLINICAL CARDIOLOGY , 编辑部邮箱 ,1998年06期
- 【分类号】R544.1
- 【下载频次】18