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苯那普利对高血压胰岛素抵抗和左室肥厚的影响

The effect of benazepril on insulin resistance and left ventricular hypertropy in patients with essential hypertension

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【作者】 李凡胡瑞玉

【Author】 Li Fan; Hu Ruiyu (Shanghai Kongjiang Red Crass Hospitel, 200093)

【机构】 上海控江红十字医院!200093

【摘要】 应用苯那普利治疗原发性高血压患者30例,剂量为3~10mg/d,疗程24周,血压从治疗前24.3/14.4kPa降至18.6/10.5kPa;治疗后的血胰岛素水平、血胰岛素/葡萄糖比值和左心室重量均较治疗前下降(均P<0.05),提示:苯那普利有明显的改善胰岛素抵抗和左心室肥厚效应。

【Abstract】 Thirty patients with essential hypertension were treated with benazepril 3-10 mg daily for 24 weeks. The results showed that there were significant difference(P <0.05) in blood pressure(24. 3/14.4 kPa vs 18. 6/10. 5 kPa),Plasma insulin level,plasma insulin/glucose ratio and left ventricular hypertropy pre-and post-treatment. It suggests that benazepril has a obvious effect on improving insulin resistance and left ventricular hypertropy in patients with essential hypertension.

  • 【文献出处】 临床心血管病杂志 ,JOURNAL OF CLINICAL CARDIOLOGY , 编辑部邮箱 ,1998年06期
  • 【分类号】R544.1
  • 【下载频次】18
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