【摘要】 目的：观察卡托普利注射液治疗高血压急症的急诊降压作用。方法：对34例高血压急症给予卡托普利注射液25mg加入5％葡萄糖20ml静注，观察注射后5、15、30、60和120min血压、心率、临床表现和不良反应。结果：用药后5minSBP和DBP即下降（P＜0．05），但以15、30、60、120min下降最明显（P＜0．01），心率略有下降（P＞0．05），总有效率91．2％。结论：卡托普利注射液降压效果明显，其急诊降压作用优于口服给药，且无明显副作用，特别适合老年人或长期高血压已产生耐受的患者，也适用于伴有急性左心衰竭或急性主动脉夹层分离的高血压急症。更多还原

【Abstract】 Objective: To investigate the antihypertensive effects of Captopril in 34 patientswith hypertensive emergency. Methods:Blood pressure and heart rate were measured at 5, 15, 30,60, 120 min after 25 mg Captopril which was dissolved in 20 ml 5% glucose was injected intra venously. Results:Systolic blood pressure (BP) and diastolic BP decreased significantly after Captopril was injected. Its effect started at 5 min after injection,the peak effect arrived at 15 min andlasted for 2 h. Total effective rate was 91. 2%. Conclusion: Captopril, (iv) is an effective acute anti-hypertensive drug. It is applicable to the patients with hypertension emergency. It may be alsoused treatment of those who complicated with left heart failure or dissecting of aorta.更多还原