【摘要】 目的：３０例小儿心内直视手术以海脉素为心肺机预充液，探讨血液稀释对小儿血球压积、血浆总蛋白、血小板及血浆电解质的影响。方法：３０例分为三组，血液稀释组（ＨＥＤ），稀释式自身输血（ＨＡＴ），输库血组（ＳＢＴ），每组１０例。观察三组麻醉前、心肺转流１５ｍｉｎ、回输机器余血１５ｍｉｎ、术后２４ｈ和７２ｈ血球压积、血浆总蛋白、血小板及血浆电解质变化。结果：心肺转流１５ｍｉｎＨＥＤ组和ＳＢＴ组呈中度、ＨＡＴ组呈中高度血液稀释。回输机器余血后，三组血球压积、血浆总蛋白均明显回升（Ｐ＜０．０５），血小板计数ＨＡＴ组高于ＨＥＤ组和ＳＢＴ组。血浆钾、钠、氯、钙离子浓度基本在正常范围。结论：小儿心内直视手术中采用海脉素血液稀释式自身输血是安全可行的。更多还原

【Abstract】 Objective: The effect of hemodilution on hematocrit, total plasma protein, electrolytes and blood platelet count was investigated. Methods:30 patients were divided into three groups:hemodilution (HED, n= 10),hemodilutional autotransfution (HAT, n= 10) and stored blood transfusion (SBT, n= 10). The changes of hematocrit, total plasma protein, electrolytes and blood platelet count were observed before anesthesia, at 15 min after the establishment of CPB,15 min after transfution with all primming machine blood, 24 and 72 hours after operation. Results: Moderate hemodilution was established in SBT group and moderate to profound in HED at 15 min after the establishment of CPB. After transfusion with all primming machine blood, total plasma protein and hematocrit increased remarkably ( P< 0 05). Blood platelet count was higher in HED group than that in HAT and SBT groups. Plasma K +, Na +,Cl - and Ca 2+ concentrations in all infants remained in the normal level during operation. After 24 hours, there was no significant difference in all parameters among the three groups. Conclusion: Hemodilutional autotransfusion with haemacel can be used safely in children undergoing open heart surgery.更多还原