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189例心脑血管病患者血清镁离子水平观察
Investigation of serum Mg2+ level in 189 patients with cardiocerebrovascular diseases
【摘要】 目的探讨血清镁离子水平与心脑血管疾病的关系。方法采用络合指示剂比色法测定66例健康人和189例各种心脑血管病患者血清中的镁离子水平。结果正常健康组为0.95±0.15mmol/L,风湿性心脑病组0.72±0.16mmol/L,冠心病组0.76±0.19mmol/L,脑梗塞组0.8±0.14mmol/L,肺原性心脏病组0.84±0.18mmol/L,冠状动脉硬化组0.77±0.23mmol/L,高血压组0.88±0.19mmol/L,脑出血组为0.9±0.2mmol/L,心肌炎组为0.87±0.14mmol/L,与健康组比较,风湿性心脏病组、冠心病和脑梗塞均有非常显著性差异(P<0.01),肺原性心脏病和冠状动脉硬化差异显著(P<0.05),高血压、脑出血和心肌炎差异无显著性(P>0.05)。结论大部分心脑血管疾病的心肌都有不同程度缺镁现象存在,测定患者血清镁离子水平能对各种心脑血管疾病有一定的诊断价值。
【Abstract】 To investigate the relation between serum magnesium ion (Mg2+ ) and cardiocerebrovascular diseases. Methods The level of serum Mg2+ in 66 healthy people and 189 patients with various kinds of cardiocerebrovascular disease were determinated by complex indicator colorimetry. Results The serum Mg2+ level of healthy pmple was 0. 96 ± 0. 05mmol/L , that of patients with rheumatic heart disease was 0. 72± 0. 16mmol/L , that with coronary disease 0. 76±0. 19mmol/L, that with cerebral infarctior 0. 8 ± 0.14mmol/L, that with cor pulmonale 0. 84± 0. 18mml/L, that with coronary atherosclerosis 0. 77±0.23mmol/L that with hypertension 0. 88 ± 0.19mmol/L, that with cerebral hemorrhage 0. 90±0. 2mml/L and that with myocarditis 0. 87 ±0 .14mmol/L respectively. There was very significant difference between healthy people and patients with rheumatic heart disease, coronary disease or cerebral infarction (P<0. 01 )significant difference between healthy peop1e and those with cor pulmonale or coroary atherosclerosis (P< 0. 05). No significant difference was shown between healthy People and patients with cerebral hemorrhage or myocarditis (P>0.05). Conclusions Various degrees of magnesium deficiency exist in the myocardium of a majority of patients with cardiocerebrovascular diseases. So, determination of patients’ serum Mg2+ level is of value to the diagnosis of such diseases.
- 【文献出处】 江西医学检验 ,JIANGXI JOURNAL OF MEDICAL LABORATORY SCIENCES , 编辑部邮箱 ,1998年02期
- 【分类号】R446.1
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