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急性心肌梗死溶栓与非溶栓治疗对比研究左心室重塑及其心功能

A study on left ventricular remodeling and cardiol function in acute myocardial infarction with or without thrombolysis therapy

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【作者】 吴伟; 郭荣利; 黄生耀;

【Author】 Wu Wei; Guo Rongli; Huang Shengyao. (Department of Emergency Medicine,First Affiliated Hospital, China Medical University, Shenyang 110001)[

【机构】 中国医科大学第一临床学院急诊科!沈阳110001; 沈阳市中心急救站;

【摘要】 目的:探讨急性前壁Q波型心肌梗死(AMI)患者左心室重塑(LVRM)和左心室收缩功能(LVSF)。方法:将140例AMI患者随机分为静脉溶栓组和非溶栓组。采用Doppler超声心动图仪进行监测。结果:140例AMI患者LVRM总发生率为42.1%。溶栓组LVRM发生率明显低于非溶栓组(P<0.05)。LVRM对LVSF产生明显影响。溶栓再通组LVRM发生率明显低于未再通组(P<0.01),且LVSF明显得到改善(P<0.01)。结论:AMI患者的LVRM发生率高,对LVSF有明显的影响。早期实施静脉溶栓治疗能减少LVRM发生,改善LVSF。

【Abstract】 Aim: To study the left ventricular remodeling (LVRM) and left ventrivcular systolic function (LVSF) in patients with acute myocardial infarction(AMI). Method: 140 patients with acute Q-type anterior myocardial infarction≤6 hours were randomly divided into thrombolysis group and non-thrombolysis group. LVRM and LVSF were studied and analysed using Doppler echocardiography. Results: The incidence of LVRM was 42.1% in 140 patients with AMI. The effect of LVRM on LVSF was obviously. In comparision with non-thrombolysis group, the incidence of LVRM was significantly decreased in thrombolysis group (p<0.05); in comparision with non-reperfusion group, the incidence of LVRM was significantly decreased (p<0.01) and LVSF was significantly improved (p<0.01) in reperfusion group. Conclusions: The incidence of LVRM high developed after AMI can affect LVSF markedly. The early intravenous thrombolysis can reduce LVRM and improve LVSF.[

  • 【文献出处】 急诊医学 ,Journal of Emergenoy Medicine , 编辑部邮箱 ,1998年05期
  • 【分类号】R542.22
  • 【被引频次】4
  • 【下载频次】34
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