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螺旋藻多糖对CD3AK细胞增殖能力的影响
THE INFLUENCE OF SPIRULINA POLYSACCHARIDE ON THE CD3AK CELLS PROLIFERATION IN VITRO
【摘要】 研究了螺旋藻多糖 ( PS)对 CD3Mc Ab激活的杀伤细胞 ( CD3Mc Ab Activated KillerCells,CD3AK Cells)增殖能力的影响。结果表明 ,当 PS浓度为 2 .5μg· ml-1培养体系条件下 ,对 CD3AK细胞具有明显的刺激细胞增殖作用 ( P<0 .0 2 ) ;对培养长达 2 3d的 CD3AK细胞杀伤肿瘤细胞 ( K562 细胞 )的活性仍维持在较高的水平 ( 4 6.5%~ 50 % )。提示 PS对辐射损伤和化疗引起的造血功能损伤及在肿瘤的生物治疗领域有较好的应用前景。
【Abstract】 We studied that the influence of spirulina polysacchride (PS) on the proliferation of CD 3AK celles were activated by CD 3McAb. The results showed that the obvious effects of celles proliferating were activated by CD 3McAb when PS was in 2.5 μg·ml -1 . The higher level of vitality of killing tumor celles (K 562 ) was kept in vitro on 23 rd day (46.5 % 50 %). These results suggest that application foreground is very well on PS against hemopoietic function injury was induced by radiotherapy and chemotherapy and in the therapy of tumors.
- 【文献出处】 海洋科学 ,MARINE SCIENCES , 编辑部邮箱 ,1998年03期
- 【分类号】Q946
- 【被引频次】16
- 【下载频次】70