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药用蚯蚓纤溶酶的制备及其性质的研究

STUDIES ON THE PREPARATION AND CHARACTERIZATION OF THE MEDICINAL FIBRINOLYTIC ENZYME FROM EARTHWORM

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【作者】 彭先凤曾蓉陈丽波杨继虞邵承斌刘开熹

【Author】 Peng Xianfeng;Zeng Rong Cheng Libo Yang Jiyu (School of Pharmacy, West China University of Medical Sciences Chengdu 610041 ) Shao Chengbin Liu Kaixi (Yuzhou University Chongqing 400000)

【机构】 华西医科大学药学院!成都610041渝州大学!重庆400000

【摘要】 从爱胜蚓中制备药用纤溶酶,经工厂中试.收率为2.52~2.74%;纤溶活性为24333~26560mm2/mg;水解酪蛋白活性为598~640mU/mg。制备工艺重复性好,操作简易可行。另报道了该酶的一些生化特性和稳定性的研究结果。

【Abstract】 The medicinal fibrinolytic enzyme from the earthworm (Eisenia Foetlide) was prepared by enlarged production. The results showed that the yield of the enzyme was 2.52-2.74%;the activity of fibrinolysis and hydrolysis casein was 24333-26560 mm2/mg and 598-640 mU/mg respectively. The re- peatability and yield were also estimated and we con- sider it might be a simple valid method for pharmaceu- tical production. In addition, this paper also reported some biochemical characterization and stability about the medicinal enzyme.

  • 【文献出处】 华西药学杂志 ,WEST CHINA JOURNAL OF PHARMACEUTCAL SCIENCES , 编辑部邮箱 ,1998年01期
  • 【分类号】R283
  • 【被引频次】7
  • 【下载频次】143
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