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药用蚯蚓纤溶酶的制备及其性质的研究
STUDIES ON THE PREPARATION AND CHARACTERIZATION OF THE MEDICINAL FIBRINOLYTIC ENZYME FROM EARTHWORM
【摘要】 从爱胜蚓中制备药用纤溶酶,经工厂中试.收率为2.52~2.74%;纤溶活性为24333~26560mm2/mg;水解酪蛋白活性为598~640mU/mg。制备工艺重复性好,操作简易可行。另报道了该酶的一些生化特性和稳定性的研究结果。
【Abstract】 The medicinal fibrinolytic enzyme from the earthworm (Eisenia Foetlide) was prepared by enlarged production. The results showed that the yield of the enzyme was 2.52-2.74%;the activity of fibrinolysis and hydrolysis casein was 24333-26560 mm2/mg and 598-640 mU/mg respectively. The re- peatability and yield were also estimated and we con- sider it might be a simple valid method for pharmaceu- tical production. In addition, this paper also reported some biochemical characterization and stability about the medicinal enzyme.
【关键词】 药用蚯蚓纤溶酶;
制备;
生化特性;
【Key words】 Medicinal fibrinolytic enzyme from earthworm Preparation Biochemical characterization;
【Key words】 Medicinal fibrinolytic enzyme from earthworm Preparation Biochemical characterization;
- 【文献出处】 华西药学杂志 ,WEST CHINA JOURNAL OF PHARMACEUTCAL SCIENCES , 编辑部邮箱 ,1998年01期
- 【分类号】R283
- 【被引频次】7
- 【下载频次】143