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2-(4,6-二甲基-2-嘧啶巯基)乙酰芳胺的合成及其生物活性的初步研究
SYNTHESES AND PRELIMINARY BIOLOGICAL ACTIVITIES TEST OF 2 (4,6 DIMETHYL 2 PYRIMIDINYLTHIO)ACETAMIDES
【摘要】 许多乙酰芳胺类化合物具有优异的生物活性,例如除草剂苯噻草胺,可抑制细胞生长和分裂,防除稻田中禾本科杂草[1];杀菌剂甲霜灵可防治作物霜霉病[2]。本文将具有多种生物活性的嘧啶基团引入到乙酰芳胺结构中[3],合成下列10个未见文献报道的标题化合物Ⅰ,通...
【Abstract】 Ten novel 2 (4,6 dimethyl 2 pyrimidinylthio) acetamides were prepared by reactions of 2 chloro acetamides with 2 mercapto 4,6 dimethylpyrimidine in butanone.Their structures were identified by IR, 1HNMR and MS.At 50mg/L in vitro.The title compounds Ⅰshowed good fungicidal activities at 1000mg/L in vivo compound “If” showed 72% and 82% control of erysiphe graminis and puccinia recondita respectively.
【关键词】 2-巯基-4`6-二甲基嘧啶;
乙酰胺;
合成;
农药;
【Key words】 mercapto 4; 6 dimethylpyrimidine; acetamide; synthesis; pesticide;
【Key words】 mercapto 4; 6 dimethylpyrimidine; acetamide; synthesis; pesticide;
- 【文献出处】 化学研究与应用 ,CHEMICAL RESEARCH AND APPLICATION , 编辑部邮箱 ,1998年05期
- 【分类号】TQ450.1
- 【被引频次】2
- 【下载频次】83