【摘要】 目的：观察药物治疗失败，采用分期手术方法获得复明的真菌性角膜溃疡病人。方法：先行结膜瓣遮盖术治愈感染性病变，六个月后再行板层角膜移植改善视功能。结果：１４例植片透明，１例半透明，１１例视力达０２～０７之间。结论：采用分期手术方法治疗真菌性角膜溃疡，手术安全，并发症少，具有不受角膜材料的限制及便于普及和推广等优点。更多还原

【Abstract】 Objective: The purpose of this study is to survey the pathogenesy of bronchial asthma and to make the clinical experiment.Methods: An airborne pollen investigation was proceeded for a year in Zhengzhou.The intracutaneous tests with inhaled antigen were done in 253 cases.The serum IgE contents were determined by ELISA in the patients with different types of bronchial asthma.LPO and SOD levels were tested in the blood and lung tissue of asthmatic guinae pigs.Two cases with difficult therapeutic asthma were treated by intravenously guttae PGE1.Results: Pollen particles are distributed year round in the air in Zhengzhou.Two peaks of pollen drifting occur from March to May,and from August to september.The intradermal skin test positive rate was 90.9% in extrinsic asthmatics.Pollens,fungi,mites and house dust were main allergens in this area.The mean serum IgE level in the extrinsic asthmatics and suffering period was much higher than that in intrinc asthmatics and relieving period.PGE1 prevents LPO levels from increasing in the lung of asthmatic guinea pigs.After intravenously guttae PGE1 treatment,lung function improved significantly and clinical symptoms disappared in the cases with difficult trerapeutic asthma.Conclusion: Bronchial asthma was in close relationship with pollen drift and allergens.The determination of serum IgE contents and lung tissue LPO levels is a matter of great signficance in asthma study.The PGE1 could be clinically valuable as a treatment of bronchial asthma.更多还原