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CA15-3RIA对乳腺癌和乳腺癌术后复发的诊断价值

Diagnostic value of CA15-3 RIA in breast cancer and its recurrence after operation

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【作者】 叶传扬章英剑朱慧娟蒋长英

【Author】 YE Chuanyang; ZHANG Yingjian; ZHU Huijuan; JIANG Changying(Cancer Hospital of Shanghai Medical University, Shanghai 200032)

【机构】 上海医科大学附属肿瘤医院!上海200032

【摘要】 用CA15I-3RIA测定了41例术前乳腺肿瘤和113例乳腺癌术后患者的血清。其中,术前25例为乳腺癌,其灵敏度为20.0%,特异性为93.7%;59例诊断为乳腺癌术后复发者,灵敏度为71.2%。50例诊断为骨转移者,灵敏度为78.0%.结果表明:由于CA15-3对早期乳腺癌的灵敏度较低,不适于作乳腺癌普查。但是,它对于乳腺癌术后复发、转移,尤其是对骨等脏器的转移具有较高的诊断价值。

【Abstract】 Serum CA15-3 levels of 41 pre-operative patients with breast tumor and 113post-operative patients with breast cancer were meassured by radioimmunoassay.The sensitivity and specificity were 20%, 93.7%, and 71.2%, respectively. In 50patients with bone metastasis, the sensitivity was 78.0%. It appears that due to itslow sensitivity for early diagnosis, CA15-3 RIA has little use for screening in generalpopulation to detect primary breast cancer in early stage but is benefical fordetecting its metastasis and recurrence.

【关键词】 CA15-3RIA(放射免疫测定)乳腺癌转移
【Key words】 CA15-3RadioimmunoassayBreast cancerMetastasis
  • 【分类号】R737.9
  • 【被引频次】2
  • 【下载频次】31
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