【摘要】 由Ｎ－乙酰四氢噻唑－２－硫酮－４－羧酸（［α］２０Ｄ－１０９．８３°），及Ｎ－苯甲酰四氢噻唑－２－硫酮－４－羧酸（［α］２０Ｄ－１１２．２２°），在Ｎ，Ｎ′－二环己基二亚胺（ＤＣＣ）存在下分别与环己胺、苯胺反应得到光学活性产物（Ｒ）－Ｎ－乙酰四氢噻唑－２－硫酮－４－甲酰环己胺（［α］１７Ｄ－７４．５°），及（Ｒ）－Ｎ－苯甲酰四氢噻唑－２－硫酮－４－甲酰苯胺（［α］１９Ｄ－７．０４°）。用量子化学ＰＭ３方法研究了反应物和产物的电子结构。更多还原

【Abstract】 (R)-N-acetylthiazolidine-2-thione-4-carbonyl cyclohexylamide 2a(17D　-74.5°), and N-benzoylthiazolidine-2-thione-4-carbonylanilide 2b(19D　-7.04°) were obtained from the dehydration of N-acetylthiazolidine-2-thione-4-carboxylic acid 1a(17D　-109.83°), or N-benzoylthiazolidine-2-thione-4-carboxylic acid 1b(19D　-112.22°), with cyclohexylamine and aniline in the presence of dicyclohexylcarbodiimide(DCC). The electronic structure of reactants and products have been studied by quantum chemistry PM3 method.更多还原